A minimum turnout clause in a referendum can have a disastrous effect, as it benefits the minority view.
The majority of voters who are against a certain proposal face two choices: vote against it (so the proposal will be rejected), or don’t vote at all (so the proposal doesn’t meet the turnout threshold). This can easily lead to a split vote where the minimum turnout is met, and the proposal is passed with the support of a minority of the electorate*.
*) this actually happened in a Dutch referendum in 2016 on the EU-Ukraine treaty, where the turnout was 32% (threshold was 30%) and 62% voted to reject the treaty, i.e. only 20% of the electorate. Opinion polls predicted that somewhere between 40% and 45% of voters were against the treaty.