I’d say if you’re looking at the Peak District: Castleton > Bakewell > Buxton…but bear in mind Castleton is small and you’d need to like rural pursuits.
If you’re a fan of Cheese and Beer I’d recommend the Wensleydale Cheese site has in Hawes and the Bkack Sheep/Theakston breweries in Masham (both in the Yorkshire Dales…or near enough in the case of Masham).
If you’re looking at cities…York, Cambridge, Oxford, Lancaster, Exeter (bit out the way) and Bath are some of the most picturesque…whereas Manchester, Leeds, Liverpool, Sheffield, Nottingham and Bristol have the biggest activity variety.