did this quite a few years ago. 3 rooms, one was landlord and his gf (now wife), it was never an issue, they were both genuinely really nice people, both really into playing and writing music outside their day jobs. the other tennants during my time were also really sound.
more interesting than that: living next door was David Mitchell
the couple i lived with have now moved elsewhere, which means i can see on zoopla how much the place sold for
purchased in 2008 for £300k and sold in 2017 for £478k
not too bad for them given that they had other people pay 2 rooms worth of mortgage during that time eh