Like I said on Brexit Day, there are no good options for Scotland now. Whatever the merits of an indy scotland at the time of the first ref, today the whole dynamic is completely different, from everything to trade, free movement, public finances (incl. oil) etc etc. People may want Scotland to stay in Europe cos of the economic benefits and free movement, but leaving a brexited UK will have much the same effect for Scotland as the UK leaving the EU.
Yet I wouldn’t wish staying in the UK on anyone.
If you really want to open a big can of worms you could talk about the effect the indyref had on the 2015 general election, and therefore Brexit. I reckon I’ll leave it though.