Probably Goldeneye on the N64, multiplayer sessions could last for hours on end. Generally had more than four players, so we’d tag in and out to let our hands recover and eat pizza
In the pre-save game era of Amiga games, you really had to book time in advance to play a game properly. Definitely played Turrican 2 for two or three hours at a time, just to have a decent go of it (got past the bit where it became an R-type game for a few levels!)