I’d struggle with it if it was my two big toes maybe.
any other toes I reckon it’d be no problem.
That said I knew a guy who lost his thumb when he was small, and they removed his big toe and put it on his thumb. Seemed to work ok as a thumb (especially as he was very young at the time so it grew with him) despite looking a little odd and he didn’t seem to struggle without his big toe.